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About 4% of adults over the age of 20 use prescription sleeping pills in the U.S., but a new study is raising eyebrows after linking these common sleep aids to dementia. The study, which was ...
Memantine. Memantine, sold under the brand name Axura among others, is a medication used to slow the progression of moderate-to-severe Alzheimer's disease. [ 7][ 8] It is taken by mouth. [ 7] Common side effects include headache, constipation, sleepiness, and dizziness. [ 7][ 8] Severe side effects may include blood clots, psychosis, and heart ...
Zolpidem is a nonbenzodiazepine or Z-drug which acts as a sedative and hypnotic. [ 10][ 16] Zolpidem is a GABA A receptor agonist of the imidazopyridine class. [ 10] It works by increasing GABA effects in the central nervous system by binding to GABA A receptors at the same location as benzodiazepines. [ 10]
Zopiclone, sold under the brand name Imovane among others, is a nonbenzodiazepine, specifically cyclopyrrolones, used to treat difficulty sleeping. Zopiclone is molecularly distinct from benzodiazepine drugs and is classed as a cyclopyrrolone. However, zopiclone increases the normal transmission of the neurotransmitter gamma-aminobutyric acid ...
The authors also investigated whether any changes in the amount of slow-wave sleep that participants got was associated with developing dementia up to 17 years after they completed the sleep studies.
Melatonin, also known as N -acetyl-5-methoxytryptamine, is a substituted tryptamine and a derivative of serotonin (5-hydroxytryptamine). It is structurally related to N-acetylserotonin (normelatonin; N -acetyl-5-hydroxytryptamine), which is the chemical intermediate between serotonin and melatonin in the body.
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