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Cell-free fetal DNA ( cffDNA) is fetal DNA that circulates freely in the maternal blood. Maternal blood is sampled by venipuncture. Analysis of cffDNA is a method of non-invasive prenatal diagnosis frequently ordered for pregnant women of advanced maternal age. Two hours after delivery, cffDNA is no longer detectable in maternal blood.
Chr. 11 p15.4. Fetal hemoglobin, or foetal haemoglobin (also hemoglobin F, HbF, or α2γ2) is the main oxygen carrier protein in the human fetus. Hemoglobin F is found in fetal red blood cells, and is involved in transporting oxygen from the mother's bloodstream to organs and tissues in the fetus. It is produced at around 6 weeks of pregnancy ...
Rh disease. Rh disease (also known as rhesus isoimmunization, Rh (D) disease, or rhesus incompatibility, and blue baby disease) is a type of hemolytic disease of the fetus and newborn (HDFN). HDFN due to anti-D antibodies is the proper and currently used name for this disease as the Rh blood group system actually has more than 50 antigens and ...
By seven weeks of gestation, the anterior pituitary vascular system begins to develop. During the first 12 weeks of gestation, the anterior pituitary undergoes cellular differentiation. At 20 weeks of gestation, the hypophyseal portal system has developed. The Rathke's pouch grows towards the third ventricle and fuses with the diverticulum.
Gestational age: 12 weeks and 0 days until 15 weeks and 6 days old. Embryonic age: 10 weeks and 0 days until 13 weeks and 6 days old. The fetus reaches a length of about 15 cm (6 in). A fine hair called lanugo develops on the head. Fetal skin is almost transparent. More muscle tissue and bones have developed, and the bones become harder.
Screening for Down syndrome by a combination of maternal age and thickness of nuchal translucency in the fetus at 11–14 weeks of gestation was introduced in the 1990s. [7] This method identifies about 75% of affected fetuses while screening about 5% of pregnancies. Natural fetal loss after positive diagnosis at 12 weeks is about 30%. [6]
Embryonic development in the human, covers the first eight weeks of development; at the beginning of the ninth week the embryo is termed a fetus. The eight weeks have 23 stages. Human embryology is the study of this development during the first eight weeks after fertilization. The normal period of gestation (pregnancy) is about nine months or ...
At 8–12 weeks of gestation, liver is a relatively bigger organ which forms 4-5-5.5% of the total body weight and protrudes through the abdominal wall. By 13 to 32 weeks of gestation, it forms 3.4% to 4.0% of the total body weight. [23] The liver weight hence forms a more or less constant proportion of the total body weight of the fetus. [24]
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