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Vasculitis [3] Alpidem (Ananxyl) 1995. Worldwide. Not approved in the US, withdrawn in France in 1994 [4] and the rest of the market in 1995 because of rare but serious hepatotoxicity. [3][5] Alosetron (Lotronex) 2000. US. Serious gastrointestinal adverse events; ischemic colitis; severe constipation. [2]
15–50% (with sudden stopping) [3][4] Antidepressant discontinuation syndrome, also called antidepressant withdrawal syndrome, is a condition that can occur following the interruption, reduction, or discontinuation of antidepressant medication following its continuous use of at least a month. [5] The symptoms may include flu-like symptoms ...
Sulfonylurea type 2 diabetes drugs are linked to a higher long-term risk of an impaired awareness of hypoglycemic episodes, according to a new study from Taiwan. From 5 years of use onward, the ...
Depression is often highly comorbid with other diseases, e.g. cardiovascular disease (myocardial infarction, [13] stroke), [14] diabetes, [15] cancer, [16] Depressed subjects are prone to smoking, [17] substance abuse, [18] eating disorders, obesity, high blood pressure, pathological gambling and internet addiction, [19] and on average have a ...
Treatment-resistant depression (TRD) is major depressive disorder in which an affected person does not respond adequately to at least two different antidepressant medications at an adequate dose and for an adequate duration. [1] Inadequate response has most commonly been defined as less than 25% reduction in depressive symptoms following ...
A major depressive episode (MDE) is a period characterized by symptoms of major depressive disorder. Those affected primarily exhibit a depressive mood for at least two weeks or more, and a loss of interest or pleasure in everyday activities. Other symptoms can include feelings of emptiness, hopelessness, anxiety, worthlessness, guilt ...
Depression, one of the most commonly diagnosed psychiatric disorders, [2] [3] is being diagnosed in increasing numbers in various segments of the population worldwide. [4] [5] Depression in the United States alone affects 17.6 million Americans each year or 1 in 6 people. Depressed patients are at increased risk of type 2 diabetes ...
Buformin also was withdrawn due to lactic acidosis risk. [11] Metformin is a first-line medication used for treatment of type 2 diabetes. It is generally prescribed at initial diagnosis in conjunction with exercise and weight loss, as opposed to the past, where it was prescribed after diet and exercise had failed.