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Duloxetine, sold under the brand name Cymbalta among others, [1] is a medication used to treat major depressive disorder, generalized anxiety disorder, obsessive-compulsive disorder, fibromyalgia, neuropathic pain and central sensitization. [7] [8] It is taken by mouth. [7] Duloxetine is a serotonin–norepinephrine reuptake inhibitor (SNRI). [9]
In Wikidata. Selective serotonin reuptake inhibitors ( SSRIs) are a class of drugs that are typically used as antidepressants in the treatment of major depressive disorder, anxiety disorders, and other psychological conditions. SSRIs increase the extracellular level of the neurotransmitter serotonin by limiting its reabsorption (reuptake) into ...
Antidepressant discontinuation syndrome, also called antidepressant withdrawal syndrome, is a condition that can occur following the interruption, reduction, or discontinuation of antidepressant medication following its continuous use of at least a month. [ 5] The symptoms may include flu-like symptoms, trouble sleeping, nausea, poor balance ...
Cymbalta (duloxetine): A medication for managing depression, anxiety, and other mental health conditions. Rozerem (ramelteon) and Hetlioz (tasimelteon): Medications that can help regulate sleep ...
How common antidepressants are linked to weight gain. The study found that the most used medications among the participant group were sertraline (Zoloft), citalopram (Celexa), and bupropion ...
Duloxetine has also been associated with cases of liver failure and should not be prescribed to patients with chronic alcohol use or liver disease. Studies have found that Duloxetine can increase liver function tests three times above their upper normal limit. [66] Patients with coronary artery disease should caution the use of SNRIs. [67]
Amitriptyline. Amitriptyline, sold under the brand name Elavil among others, is a tricyclic antidepressant primarily used to treat major depressive disorder, and a variety of pain syndromes such as neuropathic pain, fibromyalgia, migraine and tension headaches. [ 12] Due to the frequency and prominence of side effects, amitriptyline is ...
A 2014 meta-analysis from the Cochrane Collaboration found the antidepressant duloxetine to be effective for the treatment of pain resulting from diabetic neuropathy. [66] The same group reviewed data for amitriptyline in the treatment of neuropathic pain and found limited useful randomized clinical trial data.