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Liposome. Scheme of a liposome formed by phospholipids in an aqueous solution. Liposomes are composite structures made of phospholipids and may contain small amounts of other molecules. Though liposomes can vary in size from low micrometer range to tens of micrometers, unilamellar liposomes, as pictured here, are typically in the lower size ...
Cationic liposome. Cationic liposomes are spherical structures that contain positively charged lipids. Cationic liposomes can vary in size between 40 nm and 500 nm, and they can either have one lipid bilayer (monolamellar) or multiple lipid bilayers (multilamellar). [1] The positive charge of the phospholipids allows cationic liposomes to form ...
Unilamellar liposome. A unilamellar liposome is a spherical liposome, a vesicle, bounded by a single bilayer of an amphiphilic lipid or a mixture of such lipids, containing aqueous solution inside the chamber. Unilamellar liposomes are used to study biological systems and to mimic cell membranes, and are classified into three groups based on ...
A lipid nanoparticle is typically spherical with an average diameter between 10 and 1000 nanometers. Solid lipid nanoparticles possess a solid lipid core matrix that can solubilize lipophilic molecules. The lipid core is stabilized by surfactants (emulsifiers). The emulsifier used depends on administration routes and is more limited for ...
Ligand-targeted liposome. A ligand-targeted liposome (LTL) is a nanocarrier with specific ligands attached to its surface to enhance localization for targeted drug delivery. The targeting ability of LTLs enhances cellular localization and uptake of these liposomes for therapeutic or diagnostic purposes. LTLs have the potential to enhance drug ...
A liposome extruder is a device that prepares cell membranes, exosomes and also generates nanoscale liposome formulations. [1] [2] The liposome extruder employs the track-etched membrane to filter huge particles and achieve sterile filtration. [3] [4] Schematic of a monolamellar liposome.
Lipid bilayer. This fluid lipid bilayer cross section is made up entirely of phosphatidylcholine. The three main structures phospholipids form in solution; the liposome (a closed bilayer), the micelle and the bilayer. The lipid bilayer (or phospholipid bilayer) is a thin polar membrane made of two layers of lipid molecules.
Artificial cell. An artificial cell, synthetic cell or minimal cell is an engineered particle that mimics one or many functions of a biological cell. Often, artificial cells are biological or polymeric membranes which enclose biologically active materials. [ 1] As such, liposomes, polymersomes, nanoparticles, microcapsules and a number of other ...