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  2. Timeline of human vaccines - Wikipedia

    en.wikipedia.org/wiki/Timeline_of_human_vaccines

    This is a timeline of the development of prophylactic human vaccines.Early vaccines may be listed by the first year of development or testing, but later entries usually show the year the vaccine finished trials and became available on the market.

  3. ClinicalTrials.gov - Wikipedia

    en.wikipedia.org/wiki/ClinicalTrials.gov

    Headquarters. Bethesda, Maryland, U.S. Agency executive. Rebecca J. Williams, Director. Website. ClinicalTrials.gov. ClinicalTrials.gov is a registry of clinical trials. It is run by the United States National Library of Medicine (NLM) at the National Institutes of Health, and holds registrations from over 444,000 trials from 221 countries.

  4. List of clinical trial registries - Wikipedia

    en.wikipedia.org/wiki/List_of_clinical_trial...

    The DRKS is an open access, free of charge online register for clinical trials and is available both in English and German. DRKS is part of the WHO's ICTRP. The DRKS works with two partner registries in Germany, DeReG (German Registry for Somatic Gene-Transfer Trials) and Clinical Trial Registry of the University Medical Center Freiburg. [4]

  5. Open-label trial - Wikipedia

    en.wikipedia.org/wiki/Open-label_trial

    An open-label trial, or open trial, is a type of clinical trial in which information is not withheld from trial participants. [1] In particular, both the researchers and participants know which treatment is being administered. [1] This contrasts with a double-blinded trial, where information is withheld both from the researchers and the ...

  6. VISTA (protein) - Wikipedia

    en.wikipedia.org/wiki/VISTA_(protein)

    VISTA is produced at high levels in tumor-infiltrating lymphocytes, such as myeloid-derived suppressor cells and regulatory T cells, and its blockade with an antibody results in delayed tumor growth in mouse models of melanoma [13] and squamous cell carcinoma. [14] It is also up-regulated in tumour-associated macrophages in various malignancies ...

  7. Good clinical practice - Wikipedia

    en.wikipedia.org/wiki/Good_Clinical_Practice

    Good clinical practice ( GCP) is an international quality standard, which governments can then transpose into regulations for clinical trials involving human subjects. GCP follows the International Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use (ICH), and enforces tight guidelines on ethical aspects of ...

  8. Clinical trial - Wikipedia

    en.wikipedia.org/wiki/Clinical_trial

    A clinical trial participant receives an injection. Clinical trials are prospective biomedical or behavioral research studies on human participants designed to answer specific questions about biomedical or behavioral interventions, including new treatments (such as novel vaccines, drugs, dietary choices, dietary supplements, and medical devices) and known interventions that warrant further ...

  9. List of cardiovascular clinical trials - Wikipedia

    en.wikipedia.org/wiki/List_of_cardiovascular...

    Lipids. AIM-HIGH (trial) - a randomized controlled trial of niacin for increasing HDL levels. [14] HDL-Atherosclerosis Treatment Study (HATS) - a randomized controlled trial that studied people with coronary heart disease and compared a combination of simvastatin and niacin with antioxidant vitamin therapy. [15]