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Progressive retinal atrophy (PRA) is a group of genetic diseases seen in certain breeds of dogs and, more rarely, cats. Similar to retinitis pigmentosa in humans, [1] it is characterized by the bilateral degeneration of the retina, causing progressive vision loss culminating in blindness.
Leber's hereditary optic neuropathy (LHON) is a mitochondrially inherited (transmitted from mother to offspring) degeneration of retinal ganglion cells (RGCs) and their axons that leads to an acute or subacute loss of central vision; it predominantly affects young adult males.
People with vision loss from ethambutol toxicity lose vision in both eyes equally. This initially presents with problems with colors (dyschromatopsia) and can leave central visual deficits. If vision loss occurs while using ethambutol, it would be best to discontinue this medication under a doctor's supervision.
Primary glaucomas occur in the absence of other eye disease, and are therefore presumed to be genetic in origin. [1] The most common type of glaucoma in dogs is primary angle-closure glaucoma (PACG). [1] The least common type of glaucoma in dogs is primary open-angle glaucoma (POAG), although this is the most common type that affects humans. [1]
Cideciyan noted that “additional gene therapies for other rare causes of vision loss are likely to be approved for the public over the next 5 years.” View the original article on Medical News ...
For those with proliferative or severe non-proliferative diabetic retinopathy, vision loss can be prevented by treatment with panretinal laser photocoagulation. [39] The goal is to create 1,600–2,000 burns in the retina with the hope of reducing the retina's oxygen demand, and hence the possibility of ischemia. It is done in multiple sittings.
Treatment for liver shunt in dogs. The good news is that liver shunts can be treated. ... Always keep a close eye on your doggo to check for signs the condition is worsening such as vomiting ...
They have trichromatic vision, but with a smaller color gamut than typical color vision. Regarding gene therapy, they are equivalent to dichromats. Blue Cone Monochromats are missing both the L- and M-opsin and therefore have no color vision. They are treated as a subset of dichromacy since a combination of gene therapies for protanopia and ...
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