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A Clarinase Repetab tablet contains 5 mg loratadine in the tablet coating and 120 mg pseudoephedrine sulfate equally distributed between the tablet coating and the barrier-coated core. The two active components in the coating are quickly liberated; release of pseudoephedrine in the core is delayed for several hours.
Loratadine. Loratadine, sold under the brand name Claritin among others, is a medication used to treat allergies. [ 5] This includes allergic rhinitis (hay fever) and hives. [ 5] It is also available in drug combinations such as loratadine/pseudoephedrine, in which it is combined with pseudoephedrine, a nasal decongestant. [ 5]
Desloratadine. sold under the brand name Clarinex among others, is a tricyclic H 1 inverse agonist that is used to treat allergies. It is an active metabolite of loratadine. [ 6] It was patented in 1984 and came into medical use in 2001. [ 7]
A majority of an oral dose of pseudoephedrine is excreted unchanged in urine within 24 hours of administration. [11] This has been found to range from 43 to 96%. [ 1 ] [ 11 ] [ 2 ] The amount excreted unchanged is dependent on urinary pH similarly to the drug's half-life, as a longer half-life and duration in the body allows more time for the ...
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Meclizine, sold under the brand name Bonine, among others, is an antihistamine used to treat motion sickness and dizziness ( vertigo ). [ 3] It is taken by mouth. [ 3] Effects generally begin in an hour and last for up to a day. [ 3] Common side effects include sleepiness and dry mouth. [ 3] Serious side effects may include allergic reactions. [ 3]
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