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Among the best-documented probiotic strains of L. casei, L. casei DN-114001 (Actimel/DanActive) and L. casei Shirota have been extensively studied [18] and are widely available as functional foods. The genomes of these two strains have been sequenced from commercial yogurt, re-designated "LcA" and "LcY" respectively.
Bifidobacterium breve administered in combination with prebiotics or other probiotics and standard therapy has shown some beneficial effect. [5] B. breve is a constituent in the therapeutic, nutritional treatment of IBD. This proprietary, standardized, formulation of live bacteria is used to treat ulcerative colitis and may require a prescription.
BioGaia is a Swedish biotechnology company that develops, markets and sells a range of probiotic products. [1] [2] [3] It has patented the use of several Lactobacillus reuteri strains and offers gut and immune health products containing L. reuteri Protectis (DSM 17938).
FMT is an effective treatment for Clostridioides difficile infection (CDI). [3] [4] [5] For recurrent CDI, FMT is more effective than vancomycin alone, and may improve the outcome after the first index infection. [3] [5] [6] Side effects may include a risk of infections, therefore the donor should be screened for pathogens. [7]
Multidrug-resistant tuberculosis (MDR-TB) is a form of tuberculosis (TB) infection caused by bacteria that are resistant to treatment with at least two of the most powerful first-line anti-TB medications (drugs): isoniazid and rifampicin.
(Other probiotic strains used belong to the genus Bifidobacterium). [2] [14] Probiotics have been evaluated in research studies in animals and humans with respect to antibiotic-associated diarrhea, travellers' diarrhea, pediatric diarrhea, inflammatory bowel disease, irritable bowel syndrome [15] and Alzheimer's disease. [16]
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