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Testosterone is used as a medication for the treatment of male hypogonadism, gender dysphoria, and certain types of breast cancer. [13] [54] This is known as hormone replacement therapy (HRT) or testosterone replacement therapy (TRT), which maintains serum testosterone levels in the normal range.
Finasteride is a 5α-reductase inhibitor and therefore an antiandrogen. [ 10] It works by decreasing the production of dihydrotestosterone (DHT) by about 70%. [ 6] In addition to DHT, finasteride also inhibits the production of several anticonvulsant neurosteroids including allopregnanolone, androstanediol, and THDOC.
In germline gene therapy (GGT), germ cells ( sperm or egg cells) are modified by the introduction of functional genes into their genomes. Modifying a germ cell causes all the organism's cells to contain the modified gene. The change is therefore heritable and passed on to later generations.
Anabolic steroids, also known as anabolic-androgenic steroids (AAS), are a class of drugs that are structurally related to testosterone, the main male sex hormone, and produce effects by binding to the androgen receptor (AR). Anabolic steroids have a number of medical uses, [1] but are also used by athletes to increase muscle size, strength ...
July 24, 2024 at 8:13 AM. The majority of Venezuelans are religious — just like parts of the country's political history. But as they prepare for the upcoming presidential election, it's hard to ...
Androsterone, or 3α-hydroxy-5α-androstan-17-one, is an endogenous steroid hormone, neurosteroid, and putative pheromone. [1] It is a weak androgen with a potency that is approximately 1/7 that of testosterone. [2] Androsterone is a metabolite of testosterone and dihydrotestosterone (DHT). In addition, it can be converted back into DHT via 3α ...
About 10% of boys with the tumour have gynecomastia. [12] Although a Leydig cell tumour is always benign in children, it is malignant in 10% to 15% of adults. [12] It is the most common testicular cancer of non-germ cell origin. [13] Sonography may be used to identify cystic areas, but it is unable to tell benign tumours apart from malignant ...
Ten-codes, officially known as ten signals, are brevity codes used to represent common phrases in voice communication, particularly by US public safety officials and in citizens band (CB) radio transmissions. The police version of ten-codes is officially known as the APCO Project 14 Aural Brevity Code. [1]
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