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Memantine. Memantine, sold under the brand name Axura among others, is a medication used to slow the progression of moderate-to-severe Alzheimer's disease. [ 7][ 8] It is taken by mouth. [ 7] Common side effects include headache, constipation, sleepiness, and dizziness. [ 7][ 8] Severe side effects may include blood clots, psychosis, and heart ...
Melatonin, also known as N -acetyl-5-methoxytryptamine, is a substituted tryptamine and a derivative of serotonin (5-hydroxytryptamine). It is structurally related to N-acetylserotonin (normelatonin; N -acetyl-5-hydroxytryptamine), which is the chemical intermediate between serotonin and melatonin in the body.
Zopiclone, sold under the brand name Imovane among others, is a nonbenzodiazepine, specifically cyclopyrrolones, used to treat difficulty sleeping. Zopiclone is molecularly distinct from benzodiazepine drugs and is classed as a cyclopyrrolone. However, zopiclone increases the normal transmission of the neurotransmitter gamma-aminobutyric acid ...
The authors wanted to know whether chronic reductions in slow-wave sleep over time are linked with dementia risk in humans and vice versa — whether dementia-related processes in the brain may ...
Dementia with Lewy bodies (DLB) is a type of dementia characterized by changes in sleep, behavior, cognition, movement, and regulation of automatic bodily functions. Memory loss is not always an early symptom. The disease worsens over time and is usually diagnosed when cognitive impairment interferes with normal daily functioning.
Additionally, these medications were linked to a reduced the risk of dementia and also less craving for nicotine. The study is published in eClinicalMedicine , part of The Lancet Discovery Science .
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