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Cariprazine. Cariprazine, sold under the brand name Vraylar among others, is an atypical antipsychotic developed by Gedeon Richter, [ 8] which is used in the treatment of schizophrenia, bipolar mania, [ 9] bipolar depression, [ 10] and major depressive disorder. [ 6]
This can amount to considerably greater drug costs; for example, the 2016 generic drug price for TDF/FTC/EFV was $100 per patient per year, while the originator price for the same treatment was as high as $1033. [3] Furthermore, the price of originator drug costs have tended to remain static, rendering it difficult to obtain price reductions. [3]
SGLT2 inhibitor. SGLT2 inhibitors (also called gliflozins or flozins) are a class of medications that inhibit sodium-glucose transport proteins in the nephron (the functional units of the kidney ), unlike SGLT1 inhibitors that perform a similar function in the intestinal mucosa. The foremost metabolic effect of this is to inhibit reabsorption ...
Fluoxetine, sold under the brand name Prozac, among others, is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. [2] It is used for the treatment of major depressive disorder, obsessive–compulsive disorder (OCD), anxiety, bulimia nervosa, panic disorder, and premenstrual dysphoric disorder. [2]
Glatiramer acetate. Glatiramer acetate (also known as Copolymer 1, Cop-1 ), sold under the brand name Copaxone among others, is an immunomodulator medication used to treat multiple sclerosis. [ 1][ 2] Glatiramer acetate is approved in the United States to reduce the frequency of relapses, but not for reducing the progression of disability.
Topiramate, sold under the brand name Topamax among others, is a medication used to treat epilepsy and prevent migraines. [ 9] It has also been used in alcohol dependence and essential tremor. [ 9] For epilepsy this includes treatment for generalized or focal seizures. [ 10] It is taken orally (by mouth).
Ursodeoxycholic acid ( UDCA ), also known as ursodiol, is a secondary bile acid, produced in humans and most other species from metabolism by intestinal bacteria. It is synthesized in the liver in some species, and was first identified in bile of bears of genus Ursus, from which its name derived. [ 8]
Lisdexamfetamine is a substituted amphetamine with an amide linkage formed by the condensation of dextroamphetamine with the carboxylate group of the essential amino acid L -lysine. [ 22] The reaction occurs with retention of stereochemistry, so the product lisdexamfetamine exists as a single stereoisomer.
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