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The Triple Negative Breast Cancer Foundation ("TNBC Foundation" or "TNBCF") is a nonprofit organization dedicated to raising awareness of triple-negative breast cancer.The foundation supports scientists and researchers in their efforts to determine the definitive causes of triple-negative breast cancer so that effective detection, diagnosis, prevention, and treatment can be pursued and achieved.
Triple-negative breast cancer. Triple-negative breast cancer ( TNBC) is any breast cancer that either lacks or shows low levels of estrogen receptor (ER), progesterone receptor (PR) and human epidermal growth factor receptor 2 (HER2) overexpression and/or gene amplification (i.e. the tumor is negative on all three tests giving the name triple ...
Breast cancer classification divides breast cancer into categories according to different schemes criteria and serving a different purpose. The major categories are the histopathological type, the grade of the tumor, the stage of the tumor, and the expression of proteins and genes. As knowledge of cancer cell biology develops these ...
The Susan G. Komen 3-Day, frequently referred to as the 3-Day, is a 60-mile walk to raise funds for Susan G. Komen for the Cure and promote awareness to fight breast cancer. Individual participants must raise at least $2,300 to walk 60 miles (96 km) over a three-day weekend. As of 2013, the events are held in seven US cities.
Inflammatory breast cancer is a high-grade aneuploid cancer, with mutations and overexpression of p53, [ 13] high levels of E-cadherin and abnormal cadherin function. It is often regarded as a systemic cancer. A large number of IBC cases present as triple negative breast cancer (TNBC).
Each year in the United States, about 240,000 women and 2,100 men are diagnosed with breast cancer. Although the incidence rate of breast cancer is 4% lower among Black women than White women ...
Metastatic breast cancer. Metastatic breast cancer, also referred to as metastases, advanced breast cancer, secondary tumors, secondaries or stage IV breast cancer, is a stage of breast cancer where the breast cancer cells have spread to distant sites beyond the axillary lymph nodes. There is no cure for metastatic breast cancer; [ 1] there is ...
Breast cancer metastatic mouse models are experimental approaches in which mice are genetically manipulated to develop a mammary tumor leading to distant focal lesions of mammary epithelium created by metastasis. Mammary cancers in mice can be caused by genetic mutations that have been identified in human cancer.