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Preliminary trial results found a greater weight loss compared to either medication alone. HbA1c was significantly improved compared to cagrilintide alone and non-significantly better than semaglutide alone. [1] [2] In a Phase II trial, weight loss averaged -15.6 percent after 32 weeks, making CagriSema comparable in efficacy to tirzepatide.
Given that people on other prescription weight-loss medications lose, on average, 3% to 12% of their body weight after a year, it’s not surprising that semaglutide’s results are leading some ...
Semaglutide for weight loss has been in shortage since 2022, according to the FDA’s drug shortage database.Tirzepatide, which was approved for weight loss in the U.S. only in November, went into ...
These potential side effects also tend to get better once someone has been on a dosage for a while, he says. “We do have more years worth of data with semaglutide—it’s been out longer,” Dr ...
Semaglutide is an antidiabetic medication used for the treatment of type 2 diabetes and an anti-obesity medication used for long-term weight management. [ 19 ] [ 20 ] [ 21 ] It is a peptide similar to the hormone glucagon-like peptide-1 (GLP-1), modified with a side chain .
Although some GLP-1 agonists such as semaglutide are more effective than other weight loss drugs, they are still less effective than bariatric surgery in causing weight loss. [14] The weight reduction effects of GLP-1 agonists come from a combination of peripheral effects as well as activity in the brain via the central nervous system .
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