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PARP1. Poly [ADP-ribose] polymerase 1 ( PARP-1) also known as NAD+ ADP-ribosyltransferase 1 or poly [ADP-ribose] synthase 1 is an enzyme that in humans is encoded by the PARP1 gene. [ 5] It is the most abundant of the PARP family of enzymes, accounting for 90% of the NAD+ used by the family. [ 6] PARP1 is mostly present in cell nucleus, but ...
The RIL provides the system interface between the CellCore layer within the Windows Mobile OS and the radio protocol stack used by the wireless modem hardware. The RIL, therefore, also allows OEMs to integrate a variety of modems into their equipment by providing this interface. The RIL comprises two separate components: a RIL driver, which ...
alpha-1 ( α1) adrenergic receptors are G protein-coupled receptors (GPCRs) associated with the G q heterotrimeric G protein. α 1 -adrenergic receptors are subdivided into three highly homologous subtypes, i.e., α 1A -, α 1B -, and α 1D -adrenergic receptor subtypes. There is no α 1C receptor.
Programmed cell death protein 1 (PD-1), (CD279 cluster of differentiation 279). PD-1 is a protein encoded in humans by the PDCD1 gene. [5] [6] PD-1 is a cell surface receptor on T cells and B cells that has a role in regulating the immune system's response to the cells of the human body by down-regulating the immune system and promoting self-tolerance by suppressing T cell inflammatory activity.
Alpha-1 blocker. Alpha-1 blockers (also called alpha-adrenergic blocking agents or alpha-1 antagonists) constitute a variety of drugs that block the effect of catecholamines on alpha-1-adrenergic receptors. They are mainly used to treat benign prostatic hyperplasia (BPH), hypertension and post-traumatic stress disorder. [ 1]
Gravidity and parity. In biology and medicine, gravidity and parity are the number of times a female has been pregnant (gravidity) and carried the pregnancies to a viable gestational age (parity). [ 1][ 2] These two terms are usually coupled, sometimes with additional terms, to indicate more details of the female's obstetric history. [ 3]
PD-1 and PD-L1 inhibitors act to inhibit the association of the programmed death-ligand 1 ( PD-L1) with its receptor, programmed cell death protein 1 (PD-1). The interaction of these cell surface proteins is involved in the suppression of the immune system and occurs following infection to limit the killing of bystander host cells and prevent ...
View/Edit Human. View/Edit Mouse. Plasminogen activator inhibitor-1 ( PAI-1) also known as endothelial plasminogen activator inhibitor ( serpin E1) is a protein that in humans is encoded by the SERPINE1 gene. Elevated PAI-1 is a risk factor for thrombosis and atherosclerosis. [ 5]