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B vitamins are a class of water-soluble vitamins that play important roles in cell metabolism and synthesis of red blood cells. [ 1][ 2] They are a chemically diverse class of compounds. [ 1] Dietary supplements containing all eight are referred to as a vitamin B complex. Individual B vitamins are referred to by B-number or by chemical name ...
Thiamine, also known as thiamin and vitamin B 1, is a vitamin, an essential micronutrient for humans and animals. [3] [4] It is found in food and commercially synthesized to be a dietary supplement or medication. [1] [5] Phosphorylated forms of thiamine are required for some metabolic reactions, including the breakdown of glucose and amino ...
Excessive consumption of vitamins. Hypervitaminosis is a condition of abnormally high storage levels of vitamins, which can lead to various symptoms as over excitement, irritability, or even toxicity. Specific medical names of the different conditions are derived from the given vitamin involved: an excess of vitamin A, for example, is called ...
Korsakoff syndrome ( KS) [ 1] is a disorder of the central nervous system characterized by amnesia, deficits in explicit memory, and confabulation. This neurological disorder is caused by a deficiency of thiamine (vitamin B 1) in the brain, and it is typically associated with and exacerbated by the prolonged, excessive ingestion of alcohol. [ 2]
Benfotiamine. Benfotiamine ( rINN, or S-benzoylthiamine O-monophosphate) is a synthetic, fat-soluble, S -acyl derivative of thiamine (vitamin B1) that is approved in some countries as a medication or dietary supplement to treat diabetic sensorimotor polyneuropathy. Benfotiamine was developed in late 1950s in Japan. [ 1][ 2]
Wernicke encephalopathy ( WE ), also Wernicke's encephalopathy, [ 1] or wet brain is the presence of neurological symptoms caused by biochemical lesions of the central nervous system after exhaustion of B-vitamin reserves, in particular thiamine (vitamin B 1 ). [ 2] The condition is part of a larger group of thiamine deficiency disorders that ...
Thiamine pyrophosphate ( TPP or ThPP ), or thiamine diphosphate ( ThDP ), or cocarboxylase[ 1] is a thiamine (vitamin B 1) derivative which is produced by the enzyme thiamine diphosphokinase. Thiamine pyrophosphate is a cofactor that is present in all living systems, in which it catalyzes several biochemical reactions.
Thiamine deficiency. Thiamine deficiency is a medical condition of low levels of thiamine (vitamin B 1 ). [ 1] A severe and chronic form is known as beriberi. [ 1][ 7] The name beriberi was possibly borrowed in the 18th century from the Sinhalese phrase බැරි බැරි (bæri bæri, “I cannot, I cannot”), owing to the weakness ...