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  2. Promoter (genetics) - Wikipedia

    en.wikipedia.org/wiki/Promoter_(genetics)

    In genetics, a promoter is a sequence of DNA to which proteins bind to initiate transcription of a single RNA transcript from the DNA downstream of the promoter. The RNA transcript may encode a protein (mRNA), or can have a function in and of itself, such as tRNA or rRNA.

  3. Primary transcript - Wikipedia

    en.wikipedia.org/wiki/Primary_transcript

    A primary transcript is the single-stranded ribonucleic acid (RNA) product synthesized by transcription of DNA, and processed to yield various mature RNA products such as mRNAs, tRNAs, and rRNAs. The primary transcripts designated to be mRNAs are modified in preparation for translation. For example, a precursor mRNA (pre-mRNA) is a type of ...

  4. Coding region - Wikipedia

    en.wikipedia.org/wiki/Coding_region

    The coding region of a gene, also known as the coding sequence (CDS), is the portion of a gene's DNA or RNA that codes for a protein. [1] Studying the length, composition, regulation, splicing, structures, and functions of coding regions compared to non-coding regions over different species and time periods can provide a significant amount of important information regarding gene organization ...

  5. Human genome - Wikipedia

    en.wikipedia.org/wiki/Human_genome

    In 2021, scientists reported sequencing a complete, female genome (i.e., without the Y chromosome). [4] [3] The human Y chromosome, consisting of 62,460,029 base pairs from a different cell line and found in all males, was sequenced completely in January 2022. [5] The current version of the standard reference genome is called GRCh38.p14 (July ...

  6. Small interfering RNA - Wikipedia

    en.wikipedia.org/wiki/Small_interfering_RNA

    Small interfering RNA (siRNA), sometimes known as short interfering RNA or silencing RNA, is a class of double-stranded RNA at first non-coding RNA molecules, typically 20–24 (normally 21) base pairs in length, similar to miRNA, and operating within the RNA interference (RNAi) pathway. It interferes with the expression of specific genes with ...

  7. RNA - Wikipedia

    en.wikipedia.org/wiki/RNA

    Ribosomal RNA (rRNA) is the catalytic component of the ribosomes. The rRNA is the component of the ribosome that hosts translation. Eukaryotic ribosomes contain four different rRNA molecules: 18S, 5.8S, 28S and 5S rRNA. Three of the rRNA molecules are synthesized in the nucleolus, and one is synthesized elsewhere.

  8. Long non-coding RNA - Wikipedia

    en.wikipedia.org/wiki/Long_non-coding_RNA

    In 2005 the landscape of the mammalian genome was described as numerous 'foci' of transcription that are separated by long stretches of intergenic space. [6] While some long ncRNAs are located within the intergenic stretches, the majority are overlapping sense and antisense transcripts that often include protein-coding genes, [20] giving rise to a complex hierarchy of overlapping isoforms. [21]

  9. Non-coding DNA - Wikipedia

    en.wikipedia.org/wiki/Non-coding_DNA

    In bacteria, the coding regions typically take up 88% of the genome. [1] The remaining 12% does not encode proteins, but much of it still has biological function through genes where the RNA transcript is functional (non-coding genes) and regulatory sequences, which means that almost all of the bacterial genome has a function. [1]

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