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Cellulose is an example of a (1→4)-β- D -glucan composed of glucose units. Beta-glucans, β-glucans comprise a group of β- D -glucose polysaccharides ( glucans) naturally occurring in the cell walls of cereals, bacteria, and fungi, with significantly differing physicochemical properties dependent on source. Typically, β-glucans form a ...
Glucan. A glucan is a polysaccharide derived from D- glucose, [1] linked by glycosidic bonds. Glucans are noted in two forms: alpha glucans and beta glucans. Many beta-glucans are medically important. They represent a drug target for antifungal medications of the echinocandin class.
1,3-Beta-glucan synthase. 1,3-Beta-glucan synthase is a glucosyltransferase enzyme involved in the generation of beta-glucan in fungi. It serves as a pharmacological target for antifungal drugs such as caspofungin, anidulafungin, and micafungin, deemed 1,3-Beta-glucan synthase inhibitors. Under the CAZy classification system, fungi and plant ...
Glucanase. Glucanases are enzymes that break down large polysaccharides via hydrolysis. The product of the hydrolysis reaction is called a glucan, a linear polysaccharide made of up to 1200 glucose monomers, held together with glycosidic bonds. [1] Glucans are abundant in the endosperm cell walls of cereals such as barley, rye, sorghum, rice ...
Schizophyllan is a β-1,3 beta-glucan with β-1,6 branching. Schizophyllan is also known as sizofiran . Schizophyllan has a molecular weight of 450,000 Da, and a specific rotation in water of +18-24°. A chemically analogous polysaccharide, scleroglucan, is formed by the fungus Athelia rolfsii. Both polysaccharides share the chemical structure ...
Curdlan is a water-insoluble linear beta-1,3- glucan, a high-molecular-weight polymer of glucose. Curdlan consists of β- (1,3)-linked glucose residues and forms elastic gels upon heating in aqueous suspension. It was reported to be produced by Alcaligenes faecalis var. myxogenes. [1] Subsequently, the taxonomy of this non-pathogenic curdlan ...
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