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Cellulose is an example of a (1→4)-β- D -glucan composed of glucose units. Beta-glucans, β-glucans comprise a group of β- D -glucose polysaccharides ( glucans) naturally occurring in the cell walls of cereals, bacteria, and fungi, with significantly differing physicochemical properties dependent on source. Typically, β-glucans form a ...
1,3-Beta-glucan synthase. 1,3-Beta-glucan synthase is a glucosyltransferase enzyme involved in the generation of beta-glucan in fungi. It serves as a pharmacological target for antifungal drugs such as caspofungin, anidulafungin, and micafungin, deemed 1,3-Beta-glucan synthase inhibitors. Under the CAZy classification system, fungi and plant ...
Schizophyllan is a β-1,3 beta-glucan with β-1,6 branching. Schizophyllan is also known as sizofiran . Schizophyllan has a molecular weight of 450,000 Da, and a specific rotation in water of +18-24°. A chemically analogous polysaccharide, scleroglucan, is formed by the fungus Athelia rolfsii. Both polysaccharides share the chemical structure ...
Glucan 1,3-β-glucosidase ( EC 3.2.1.58, exo-1,3-β-glucosidase, β-1,3-glucan exo-hydrolase, exo (1→3)-glucanohydrolase, 1,3-β-glucan glucohydrolase) is an enzyme with systematic name 3-β-D-glucan glucohydrolase. [1] [2] It catalyses the successive hydrolysis of β- D - glucose units from the non-reducing ends of (1→3)-β- D -glucans ...
Glucanase. Glucanases are enzymes that break down large polysaccharides via hydrolysis. The product of the hydrolysis reaction is called a glucan, a linear polysaccharide made of up to 1200 glucose monomers, held together with glycosidic bonds. [1] Glucans are abundant in the endosperm cell walls of cereals such as barley, rye, sorghum, rice ...
Lentinan is a β-1,3 beta-glucan with β-1,6 branching. It has a molecular weight of 500,000 Da and specific rotation of +14-22° (NaOH).
β-Glucosidase ( EC 3.2.1.21; systematic name β-D-glucoside glucohydrolase) is an enzyme that catalyses the following reaction: [ 2] Hydrolysis of terminal, non-reducing β- D -glucosyl residues with release of β- D -glucose.
A glucan is a polysaccharide derived from D- glucose, [1] linked by glycosidic bonds. Glucans are noted in two forms: alpha glucans and beta glucans. Many beta-glucans are medically important. They represent a drug target for antifungal medications of the echinocandin class.
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