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Ramelteon, sold as Rozerem and others, is a medication that acts on melatonin receptors to improve sleep onset in adults with insomnia. It is not a controlled substance, but its effectiveness and benefits are controversial and small.
Suvorexant, sold as Belsomra, is a medication for insomnia that acts by blocking orexin receptors in the brain. It helps with sleep onset and maintenance, but may cause side effects such as somnolence, headache, and abnormal dreams.
Eszopiclone, sold as Lunesta and others, is a medication used to treat insomnia. It is a nonbenzodiazepine or Z-drug and a cyclopyrrolone that works by interacting with GABA receptors. It is a controlled substance in the US, but not in the EU.
For people who have a hard time falling or staying asleep: the U.S. Food and Drug Administration announced the approval of a new sleep aide that works differently from other drugs on the market ...
Zolpidem, sold under the brand name Ambien among others, is a nonbenzodiazepine sedative-hypnotic that acts on GABA receptors in the brain. It is used for short-term treatment of sleeping problems, but has side effects such as daytime sleepiness, memory problems, and hallucinations.
Modafinil, sold under the brand name Provigil among others, is used to treat narcolepsy, sleep apnea, and shift work sleep disorder. It is a CNS stimulant with low addiction liability, but also has potential for allergic reactions, mental effects, and interactions with other drugs.
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