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Cardiac cells have two refractory periods, the first from the beginning of phase 0 until part way through phase 3; this is known as the absolute refractory period during which it is impossible for the cell to produce another action potential. This is immediately followed, until the end of phase 3, by a relative refractory period, during which a ...
Cardiac physiology. Cardiac physiology or heart function is the study of healthy, unimpaired function of the heart: involving blood flow; myocardium structure; the electrical conduction system of the heart; the cardiac cycle and cardiac output and how these interact and depend on one another.
The Frank–Starling law is named after the two physiologists, Otto Frank and Ernest Henry Starling. However, neither Frank nor Starling was the first to describe the relationship between the end-diastolic volume and the regulation of cardiac output. [ 5] The first formulation of the law was theorized by the Italian physiologist Dario Maestrini ...
The cardiac conduction system ( CCS, also called the electrical conduction system of the heart) [ 1] transmits the signals generated by the sinoatrial node – the heart 's pacemaker, to cause the heart muscle to contract, and pump blood through the body's circulatory system. The pacemaking signal travels through the right atrium to the ...
The beta-1 adrenergic receptor (β 1 adrenoceptor), also known as ADRB1, can refer to either the protein-encoding gene (gene ADRB1) or one of the four adrenergic receptors. [5] It is a G-protein coupled receptor associated with the Gs heterotrimeric G-protein that is expressed predominantly in cardiac tissue. In addition to cardiac tissue, beta ...
Cardiovascular physiology. Cardiovascular physiology is the study of the cardiovascular system, specifically addressing the physiology of the heart ("cardio") and blood vessels ("vascular"). These subjects are sometimes addressed separately, under the names cardiac physiology and circulatory physiology. [1]
The cardiovascular centre, or cardiovascular center, is part of the medulla oblongata of the brainstem. [ 1][ 2] Normally, the heart beats without nervous control. In some situations, such as exercise, and major trauma, the cardiovascular centre is responsible for altering heart rate. It also mediates respiratory sinus arrhythmia .
Cardiac function curve. A cardiac function curve is a graph showing the relationship between right atrial pressure (x-axis) and cardiac output (y-axis). [citation needed] Superimposition of the cardiac function curve and venous return curve is used in one hemodynamic model. [ 1]