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Ketogenesis is the biochemical process through which organisms produce ketone bodies by breaking down fatty acids and ketogenic amino acids. [ 1][ 2] The process supplies energy to certain organs, particularly the brain, heart and skeletal muscle, under specific scenarios including fasting, caloric restriction, sleep, [ 3] or others.
Ketogenic diet. Testing for ketone bodies in urine. The ketogenic diet is a high-fat, adequate- protein, low-carbohydrate dietary therapy that in conventional medicine is used mainly to treat hard-to-control (refractory) epilepsy in children. The diet forces the body to burn fats rather than carbohydrates .
α-Ketoglutaric acid (also termed 2-oxoglutaric acid) is a dicarboxylic acid, i.e., a short-chain fatty acid containing two carboxyl groups (carboxy groups notated as CO2H) with C, O, and H standing for carbon, oxygen, and hydrogen, respectively (see adjacent figure). However, almost all animal tissues and extracellular fluids have a pH above 7.
In organic chemistry, keto acids or ketoacids (also called oxo acids or oxoacids) are organic compounds that contain a carboxylic acid group ( −COOH) and a ketone group ( >C=O ). [1] In several cases, the keto group is hydrated. The alpha-keto acids are especially important in biology as they are involved in the Krebs citric acid cycle and in ...
The original ketogenic diet is a high-fat, low-carbohydrate diet developed in the 1920s and used to treat drug-resistant childhood epilepsy. [73] [74] Most epilepsy specialists order these children to eat 80% of the diet from fat by weight (90% of calories), plus carbohydrate-free vitamins and minerals to prevent vitamin deficiency. [75]
Intermittent fasting: Cycling between non- fasting and fasting as a method of calorie restriction. [ 16] Body for Life: A calorie-control diet, promoted as part of the 12-week Body for Life program. [ 17] Cookie diet: A calorie control diet in which low-fat cookies are eaten to quell hunger, often in place of a meal.
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