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Lonapegsomatropin. Lonapegsomatropin, sold under the brand name Skytrofa, is a human growth hormone used for the treatment of growth hormone deficiency. [1] [3] Lonapegsomatropin is a prodrug of somatropin. [1] Lonapegsomatropin was approved for medical use in the United States in August 2021, [1] [2] [5] and in the European Union in January 2022.
Growth hormone. Growth hormone ( GH) or somatotropin, also known as human growth hormone ( hGH or HGH) in its human form, is a peptide hormone that stimulates growth, cell reproduction, and cell regeneration in humans and other animals. It is thus important in human development. GH also stimulates production of Insulin-like growth factor 1 (IGF ...
Growth hormone is a peptide hormone secreted by the pituitary gland that stimulates growth and cell reproduction. In the past, growth hormone was extracted from human pituitary glands. Growth hormone is now produced by recombinant DNA technology and is prescribed for a variety of reasons. GH therapy has been a focus of social and ethical ...
Somapacitan. Somapacitan, sold under the brand name Sogroya, is a growth hormone medication. [3] [10] Somapacitan is a human growth hormone analog. [3] Somapacitan-beco is produced in Escherichia coli by recombinant DNA technology. [3] The most common side effects include: back pain, joint paint, indigestion, a sleep disorder, dizziness ...
Saizen is a commercial preparation of synthetic somatropin ( growth hormone, a.k.a. GH) used for growth hormone treatment. Manufactured by Merck Serono, Saizen is produced by recombinant DNA technology from a mammalian cell line (mouse C127) that was modified by the addition of the human GH gene, resulting in an identical 191- amino acid ...
Somatrem is a recombinant human growth hormone used for the treatment of short stature due to decreased or absent secretion of endogenous growth hormone. Somatrem was first marketed under the brand name Protropin by Genentech in 1985. [2] It differs from endogenous growth hormone by the addition of an extra methionine at the N-terminus [3 ...
Somatrogon, sold under the brand name Ngenla, is a medication for the treatment of growth hormone deficiency. [1] [6] [8] Somatrogon is a glycosylated protein constructed from human growth hormone and a small part of human chorionic gonadotropin which is appended to both the N-terminal and C-terminal. [8] Somatrogon is a human growth hormone ...
Growth-hormone-releasing hormone is the lead compound for a number of structural and functional analogs, such as Pro-Pro-hGHRH (1-44)-Gly-Gly-Cys, [7] CJC-1293, [8] and CJC-1295. [9] Many GHRH analogs remain primarily research chemicals, although some have specific applications. Sermorelin, a functional peptide fragment of GHRH, has been used ...
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