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FBXL2. F-box/LRR-repeat protein 2 is a protein that in humans is encoded by the FBXL2 gene. [4] [5] [6] This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1 ...
FBXO2. F-box only protein 2 is a protein that in humans is encoded by the FBXO2 gene. [5] [6] [7] This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1 ...
F-box domain is a protein structural motif of about 50 amino acids that mediates protein–protein interactions. It has consensus sequence and varies in few positions. It was first identified in cyclin F. [ 2] The F-box motif of Skp2, consisting of three alpha-helices, interacts directly with the SCF protein Skp1. [ 3]
Skp, Cullin, F-box containing complex (or SCF complex) is a multi-protein E3 ubiquitin ligase complex that catalyzes the ubiquitination of proteins destined for 26S proteasomal degradation. [1] Along with the anaphase-promoting complex, [2] SCF has important roles in the ubiquitination of proteins involved in the cell cycle.
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Members of the F-box protein family, such as FBXO15, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1, cullin, and F-box proteins, act as protein- ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction ...
The Dark Knight Rises. The Dark Knight Rises is a 2012 superhero film directed by Christopher Nolan, who co-wrote the screenplay with his brother Jonathan, and the story with David S. Goyer. [ 5] Based on the DC Comics character Batman, it is the final installment in Nolan's The Dark Knight trilogy, and the sequel to The Dark Knight (2008).
Fox Broadcasting Company, LLC, [ 1] commonly known simply as Fox and stylized in all caps, [ 2] is an American commercial broadcast television network owned by the Fox Entertainment division of Fox Corporation and The Walt Disney Company, headquartered at 1211 Avenue of the Americas in Midtown Manhattan. Fox hosts additional offices at the Fox ...