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Constitutional Symptoms. Unexplained weight loss: Weight loss that is unintended and not explained by diet, exercise or other illness may be a warning sign of many types of cancer. Unexplained pain: Pain that persists, has no clear cause, and does not respond to treatment may be a warning sign of many types of cancers.
The HAIR-AN syndrome is a rare subtype of polycystic ovary syndrome (PCOS) characterized by hyperandrogenism (HA), insulin resistance (IR) and acanthosis nigricans (AN). The symptoms of the HAIR-AN syndrome are largely due to severe insulin resistance, which can be secondary to blocking antibodies against the insulin receptor or genetically absent/reduced insulin receptor number/function.
Hard lump with a scaly top or ulceration. [ 1] Cutaneous squamous-cell carcinoma ( cSCC ), also known as squamous-cell carcinoma of the skin or squamous-cell skin cancer, is one of the three principal types of skin cancer, alongside basal-cell carcinoma and melanoma. [ 10] cSCC typically presents as a hard lump with a scaly surface, though it ...
Menkes disease. Menkes disease ( MNK ), also known as Menkes syndrome, [ 1][ 2] is an X-linked recessive disorder caused by mutations in genes coding for the copper-transport protein ATP7A, [ 3] leading to copper deficiency. [ 4][ 5] Characteristic findings include kinky hair, growth failure, and nervous system deterioration.
A Pancoast tumor is a tumor of the apex of the lung. It is a type of lung cancer defined primarily by its location situated at the top end of either the right or left lung. It typically spreads to nearby tissues such as the ribs and vertebrae. Most Pancoast tumors are non-small-cell lung cancers . The growing tumor can cause compression of many ...
Uncombable hair syndrome ( UHS) is a rare structural anomaly of the hair with a variable degree of effect. It is characterized by hair that is silvery, dry, frizzy, wiry, and impossible to comb. [ 4] It was first reported in the early 20th century. [ 5] It typically becomes apparent between the ages of 3 months and 12 years. [ 6]
Mayo Clinic is a nonprofit hospital system with campuses in Rochester, Minnesota; Scottsdale and Phoenix, Arizona; and Jacksonville, Florida. [ 22][ 23] Mayo Clinic employs 76,000 people, including more than 7,300 physicians and clinical residents and over 66,000 allied health staff, as of 2022. [ 5] In addition, Mayo Clinic partially owns and ...
Skin cancers are cancers that arise from the skin. They are due to the development of abnormal cells that have the ability to invade or spread to other parts of the body. [ 10] Skin cancer is the most commonly diagnosed form of cancer in humans. [ 11][ 12][ 13] There are three main types of skin cancers: basal-cell skin cancer (BCC), squamous ...
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