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CYP3A4 promotes the growth of various types of human cancer cell lines in culture by producing (±)-14,15-epoxyeicosatrienoic acids, which stimulate these cells to grow.[9] The CYP3A4 enzyme is also reported to have fatty acid monooxgenase activity for metabolizing arachidonic acid to 20-Hydroxyeicosatetraenoic acid(20-HETE).
Tumor metabolome. Tumor metabolome: Relationships between metabolome, proteome, and genome in cancerous cells. Glycolysis breaks down glucose into pyruvate, which is then fermented to lactate; pyruvate flux through TCA cycle is down-regulated in cancer cells. Pathways branching off of glycolysis, such as the pentose phosphate pathway, generate ...
The enzyme phospholipase A2 (EC 3.1.1.4, PLA2, systematic name phosphatidylcholine 2-acylhydrolase) catalyses the cleavage of fatty acids in position 2 of phospholipids, hydrolyzing the bond between the second fatty acid “tail” and the glycerol molecule: phosphatidylcholine + H 2 O = 1-acylglycerophosphocholine + a carboxylate.
Having a healthy diet, with foods like blueberries, avocado and nuts, is linked with better brain function, research finds. (Getty) (Liudmila Chernetska via Getty Images)
Turbo cancer is an anti-vaccination conspiracy theory [1] alleging that people vaccinated against COVID-19, especially with mRNA vaccines, are suffering from a high incidence of fast-developing cancers.
Carcinogenesis, also called oncogenesis or tumorigenesis, is the formation of a cancer, whereby normal cells are transformed into cancer cells. The process is characterized by changes at the cellular, genetic, and epigenetic levels and abnormal cell division. Cell division is a physiological process that occurs in almost all tissues and under a ...
Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body. [2] [7] These contrast with benign tumors, which do not spread. [7] Possible signs and symptoms include a lump, abnormal bleeding, prolonged cough, unexplained weight loss, and a change in bowel movements. [1] While these symptoms may indicate cancer, they can also ...
Bee Swarm Simulator. Bee Swarm Simulator is an incremental game developed by Onett where bees follow players around. The bees help collect pollen to convert into honey [12] and attack hostile mobs. [13] The game uses quests, events and other features to hook its players into continuing to play the game.