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Oncology, endocrine surgery. Multiple endocrine neoplasia type 1 (MEN-1) is one of a group of disorders, the multiple endocrine neoplasias, that affect the endocrine system through development of neoplastic lesions in pituitary, parathyroid gland and pancreas. [ 1] Individuals suffering from this disorder are prone to developing multiple ...
Multiple Endocrine Neoplasia type 1 (MEN1) is a rare hereditary endocrine cancer syndrome characterized primarily by tumors of the parathyroid glands (95% of cases), endocrine gastroenteropancreatic (GEP) tract (30–80% of cases), and anterior pituitary (15–90% of cases). [19] Other endocrine and non-endocrine neoplasms including ...
Autoimmune polyendocrine syndrome type 1 ( APS-1 ), is a subtype of autoimmune polyendocrine syndrome (autoimmune polyglandular syndrome). It causes the dysfunction of multiple endocrine glands due to autoimmunity. It is a genetic disorder, inherited in autosomal recessive fashion due to a defect in the AIRE gene (autoimmune regulator), which ...
Zollinger–Ellison syndrome. Zollinger–Ellison syndrome ( Z-E syndrome) is rare disease in which tumors cause the stomach to produce too much acid, resulting in peptic ulcers. Symptoms include abdominal pain and diarrhea . The syndrome is caused by a gastrinoma, a neuroendocrine tumor that secretes a hormone called gastrin. [ 2]
MEN1. Menin is a protein that in humans is encoded by the MEN1 gene. [ 5] Menin is a putative tumor suppressor associated with multiple endocrine neoplasia type 1 (MEN-1 syndrome) and has autosomal dominant inheritance. [ 6] Variations in the MEN1 gene can cause pituitary adenomas, hyperparathyroidism, pancreatic neuroendocrine tumors ...
Generalized anxiety disorder ( GAD) is a mental and behavioral disorder, [ 5] specifically an anxiety disorder characterized by excessive, uncontrollable and often irrational worry about events or activities. [ 6] Worry often interferes with daily functioning, and individuals with GAD are often overly concerned about everyday matters such as ...
XYY syndrome, also known as Jacobs syndrome, is an aneuploid genetic condition in which a male has an extra Y chromosome. [1] There are usually few symptoms. [2] These may include being taller than average and an increased risk of learning disabilities. [1] [2] The person is generally otherwise normal, including typical rates of fertility. [1]
Medically, dyspareunia is a pelvic floor dysfunction and is frequently underdiagnosed. [ 2] It can affect a small portion of the vulva or vagina or be felt all over the surface. Understanding the duration, location, and nature of the pain is important in identifying the causes of the pain. Numerous physical, psychological, and social or ...