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Suvorexant is used for the treatment of insomnia, characterized by difficulties with sleep onset and/or sleep maintenance, in adults. [2] [6] At a dose of 15 to 20 mg and in terms of treatment–placebo difference, it reduces time to sleep onset by up to 10 minutes, reduces time awake after sleep onset by about 15 to 30 minutes, and increases total sleep time by about 10 to 20 minutes. [2]
Ramelteon is taken by mouth. [ 3] Side effects of ramelteon include somnolence, dizziness, fatigue, nausea, exacerbated insomnia, and changes in hormone levels. [ 3] Ramelteon is an analogue of melatonin and is a selective agonist of the melatonin MT 1 and MT 2 receptors. [ 3] The half-life and duration of ramelteon are much longer than those ...
Zolpidem is a nonbenzodiazepine or Z-drug which acts as a sedative and hypnotic. [ 10][ 16] Zolpidem is a GABA A receptor agonist of the imidazopyridine class. [ 10] It works by increasing GABA effects in the central nervous system by binding to GABA A receptors at the same location as benzodiazepines. [ 10]
Ozempic is a prescription injectable medication approved by the U.S. Food and Drug Administration (FDA) in the management of type 2 diabetes, but is also used off-label to aid weight loss.
Doxylamine succinate is the active ingredient in many over-the-counter sleep-aids branded under various names. Doxylamine succinate and pyridoxine (Vitamin B6) are the ingredients of Diclegis, approved by the FDA in April 2013 becoming the only drug approved for morning sickness [46] with a class A safety rating for pregnancy (no evidence of risk).
Ketamine, an anesthetic and mental health medication, is known for its rapid antidepressant effects. It significantly impacts sleep, often reducing REM and slow-wave sleep, and isn't typically ...
Side effects of daridorexant include headache, somnolence, and fatigue. [1] [7] The medication is a dual orexin receptor antagonist (DORA). [9] [7] [10] [8] It acts as a selective dual antagonist of the orexin receptors OX 1 and OX 2. [9] [10] [8] Daridorexant has a relatively short elimination half-life of 8 hours and a time to peak of about 1 ...
Hydroxyzine. Hydroxyzine, sold under the brand names Atarax and Vistaril among others, is an antihistamine medication. [ 8] It is used in the treatment of itchiness, insomnia, anxiety, and nausea, including that due to motion sickness. [ 8] It is used either by mouth or injection into a muscle. [ 8]
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