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Radiation-induced cancer. Exposure to ionizing radiation is known to increase the future incidence of cancer, particularly leukemia. The mechanism by which this occurs is well understood, but quantitative models predicting the level of risk remain controversial. The most widely accepted model posits that the incidence of cancers due to ionizing ...
Cancer slope factors (CSF) are used to estimate the risk of cancer associated with exposure to a carcinogenic or potentially carcinogenic substance. A slope factor is an upper bound, approximating a 95% confidence limit , on the increased cancer risk from a lifetime exposure to an agent by ingestion or inhalation .
The linear no-threshold model (LNT) is a dose-response model used in radiation protection to estimate stochastic health effects such as radiation-induced cancer, genetic mutations and teratogenic effects on the human body due to exposure to ionizing radiation. The model assumes a linear relationship between dose and health effects, even for ...
The result is a lifetime risk and a five-year risk based on factors that have been tied to a higher risk of breast cancer. For comparison, it also gives an average risk for U.S. women of the same ...
Radiation hormesis. Alternative assumptions for the extrapolation of the cancer risk vs. radiation dose to low-dose levels, given a known risk at a high dose: supra-linearity (A), linear (B), linear-quadratic (C) and hormesis (D). Radiation hormesis is the hypothesis that low doses of ionizing radiation (within the region of and just above ...
Only about 350 out of every 100,000 cases of cancer diagnosed each year are found in people between ages 45 and 49, according to the National Cancer Institute. “It’s not something that people ...
The NCI-60 cancer cell line panel is a group of 60 human cancer cell lines used by the National Cancer Institute (NCI) for the screening of compounds to detect potential anticancer activity. [ 1 ] Purpose
This means that a person living in an average European dwelling with 50 Bq/m 3 has a lifetime excess lung cancer risk of 1.5–3 × 10 −3. Similarly, a person living in a dwelling with a high radon concentration of 1000 Bq/m 3 has a lifetime excess lung cancer risk of 3–6%, implying a doubling of background lung cancer risk. [63]