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Adipsia, also known as hypodipsia, is a symptom of inappropriately decreased or absent feelings of thirst. [1] [2] It involves an increased osmolality or concentration of solute in the urine, which stimulates secretion of antidiuretic hormone (ADH) from the hypothalamus to the kidneys. This causes the person to retain water and ultimately ...
The areas of the brain that contribute to the sense of thirst are mainly located in the midbrain and the hindbrain. Specifically, the hypothalamus appears to play a key role in the regulation of thirst. The area postrema and nucleus tractus solitarii signal to the subfornical organ and to the lateral parabrachial nucleus. [2]
Excessive urination and extreme thirst and increased fluid intake (especially for cold water and sometimes ice or ice water) are typical for DI. [7] The symptoms of excessive urination and extreme thirst are similar to what is seen in untreated diabetes mellitus, with the distinction that the urine does not contain glucose. Blurred vision is a ...
The hypothalamus ( pl.: hypothalami; from Ancient Greek ὑπό (hupó) 'under' and θάλαμος (thálamos) 'chamber') is a small part of the vertebrate brain that contains a number of nuclei with a variety of functions. One of the most important functions is to link the nervous system to the endocrine system via the pituitary gland.
Hypernatremia, also spelled hypernatraemia, is a high concentration of sodium in the blood. [3] Early symptoms may include a strong feeling of thirst, weakness, nausea, and loss of appetite. [1] Severe symptoms include confusion, muscle twitching, and bleeding in or around the brain. [1] [2] Normal serum sodium levels are 135–145 mmol/L (135 ...
The median preoptic nucleus is located along the midline in a position significantly dorsal to the other three preoptic nuclei, at least in the crab-eating macaque brain. It wraps around the top (dorsal), front, and bottom (ventral) surfaces of the anterior commissure. The median preoptic nucleus generates thirst.
The area postrema is a paired protuberance found at the inferoposterior limit of the fourth ventricle. [ 1][ 5] Specialized ependymal cells are found within the area postrema. These cells differ slightly from the majority of ependymal cells (ependymocytes), forming a unicellular epithelial lining of the ventricles and central canal.
Neurology, endocrinology. Hypothalamic disease is a disorder presenting primarily in the hypothalamus, which may be caused by damage resulting from malnutrition, including anorexia and bulimia eating disorders, [1] [2] genetic disorders, radiation, surgery, head trauma, [3] lesion, [1] tumour or other physical injury to the hypothalamus.