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Loratadine. Loratadine, sold under the brand name Claritin among others, is a medication used to treat allergies. [ 5] This includes allergic rhinitis (hay fever) and hives. [ 5] It is also available in drug combinations such as loratadine/pseudoephedrine, in which it is combined with pseudoephedrine, a nasal decongestant. [ 5]
A Clarinase Repetab tablet contains 5 mg loratadine in the tablet coating and 120 mg pseudoephedrine sulfate equally distributed between the tablet coating and the barrier-coated core.
Pseudoephedrine has been used in the form of the hydrochloride and sulfate salts and in a polistirex form. [29] The drug has been used in more than 135 over-the-counter and prescription formulations. [22] Many prescription formulations containing pseudoephedrine have been discontinued over time. [29]
Gel permeation chromatography. Gel permeation chromatography ( GPC) [ 1] is a type of size-exclusion chromatography (SEC), that separates high molecular weight or colloidal analytes on the basis of size or diameter, typically in organic solvents. The technique is often used for the analysis of polymers. As a technique, SEC was first developed ...
Starch gelatinization. Starch gelatinization is a process of breaking down of intermolecular bonds of starch molecules in the presence of water and heat, allowing the hydrogen bonding sites (the hydroxyl hydrogen and oxygen) to engage more water. This irreversibly dissolves the starch granule in water. Water acts as a plasticizer.
Pharmaceutical formulation. Pharmaceutical formulation, in pharmaceutics, is the process in which different chemical substances, including the active drug, are combined to produce a final medicinal product. The word formulation is often used in a way that includes dosage form .
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